Nimble is using its unique maskless chemical synthesis platform to synthesize and systematically discover novel medicines in a variety of therapeutic areas.
Nimble harnesses the power of photolithography and an extensive library of photoprotected amino acids to enable the design, synthesis, and screening of millions of diverse macrocycles at unprecedented speed.
Lead peptides are systematically engineered using the vast scale and chemical diversity of our amino acid library. Our catalog of photoprotected amino acids span both natural and non-natural amino acids including L-, D-, beta, gamma, and N-methyl monomers. We incorporate additional chemical reactions and orthogonal protecting groups to access unique molecular architectures . Nimble libraries are systematically designed using chemical matter that is either discovered or designed specifically with a target's profile in mind.