Nimble Therapeutics

Technology

 

Nimble is using its unique maskless chemical synthesis platform to synthesize and systematically discover novel medicines in a variety of therapeutic areas. 

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Nimble harnesses the power of photolithography and an extensive library of photoprotected amino acids to enable the design, synthesis, and screening of millions of diverse macrocycles at unprecedented speed. 

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Lead peptides are systematically engineered using the vast scale and chemical diversity of our amino acid library. Our catalog of photoprotected amino acids span both natural and non-natural amino acids including L-, D-, beta, gamma, and N-methyl monomers. We incorporate additional chemical reactions and orthogonal protecting groups to access unique molecular architectures . Nimble libraries are systematically designed using chemical matter that is either discovered or designed specifically with a target's profile in mind.

 
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